OpenSplice

OpenSplice ExonExplorer

Interactive static browser version of the OpenSplice paper companion app. Select an exon, switch between delta PSI and PSI views, and inspect complementary sequence and ClinVar plots below.

Cell line

Search by exon ID, gene name, or hg38 exon coordinates.

Exon -
WT PSI -

Exon metadata

Heatmap

Delta PSI or PSI view for the selected exon.

Heatmap scale

Heatmap controls also update the filtered rows table. Mutation-class toggles also affect the SpliceMaps variant panel.

WT nucleotide importance logo

-Mean∆Logit > 0 important for inclusion;-Mean∆Logit < 0 important for skipping.

SpliceMaps variants

Mutation-level map with substitution points and deletion segments.

Show:

SpliceMaps profile

Median, minimum, and maximum profile with SRE regions.

ClinVar lollipop

Shown only when ClinVar annotations are available for the selected exon.

Data table

Search or scroll through the currently visible heatmap rows.